According
to 2010 National Health Interview Survey (NHIS), 12.8% adults in USA were taking
NSAIDS at least three times per week for 3 months, that is 40% more as compared to
an equivalent study that was drained in 2005. But the main reason of concern is, according
to a telephone survey 26% of OTC NSAIDS users were taking additional dose than the recommended. Long
term use of NSAIDS has been reported to cause more cases of ulcer, bloating, reflux, belching, and/or nausea compared
with non-users. A prospective observational
study found that bleeding complications occurred without typical ulcer symptoms
(epigastric pain or dyspepsia) in up to 80% of affected patients

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